[Nitroglycerin and amyl nitrite action on common bile duct during operation for vesicular lithiasis (author's transl)]

Anesth Analg (Paris). 1979;36(11-12):557-60.
[Article in French]

Abstract

Eight patients undergoing cholecystectomy received a single injection of nitroglycerin (0,9 mg) and 8 received amyl nitrite, during a cholangio-kinesimetry. The maximum fall in common bile duct pressure was similar in both group; 3.2 +/- 0.3 torr after nitroglycerin (NTG),3.8 +/- 0.6 torr after amyl nitrite (AN). NTG caused a more persistent lowering of pressure than AN; 614 +/- 42 seconds/343 +/- 27 seconds (p < 0.001). This study showed that it is possible to produce a relaxation of biliary tract muscle fibres with an injection of nitroglycerin and then replace amyl nitrite during anesthesia.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Aged
  • Amyl Nitrite / pharmacology*
  • Cholelithiasis / surgery*
  • Common Bile Duct / drug effects*
  • Common Bile Duct / surgery
  • Female
  • Humans
  • Male
  • Middle Aged
  • Nitroglycerin / pharmacology*
  • Pressure

Substances

  • Amyl Nitrite
  • Nitroglycerin