High-dose methotrexate with citrovorum factor rescue and adriamycin in childhood osteogenic sarcoma

Cancer. 1974 Apr;33(4):1151-63. doi: 10.1002/1097-0142(197404)33:4<1151::aid-cncr2820330439>3.0.co;2-8.
No abstract available

MeSH terms

  • Adolescent
  • Age Factors
  • Alkaline Phosphatase / blood
  • Aspartate Aminotransferases / blood
  • Bone Neoplasms / drug therapy*
  • Bone Neoplasms / enzymology
  • Child
  • Doxorubicin / administration & dosage
  • Doxorubicin / therapeutic use*
  • Drug Therapy, Combination
  • Evaluation Studies as Topic
  • Female
  • Hematopoietic System / drug effects
  • Humans
  • Leucovorin / administration & dosage
  • Leucovorin / therapeutic use*
  • Male
  • Methotrexate / administration & dosage
  • Methotrexate / adverse effects
  • Methotrexate / therapeutic use*
  • Mucous Membrane / drug effects
  • Nausea / chemically induced
  • Neoplasm Metastasis
  • Osteosarcoma / drug therapy*
  • Osteosarcoma / enzymology

Substances

  • Doxorubicin
  • Aspartate Aminotransferases
  • Alkaline Phosphatase
  • Leucovorin
  • Methotrexate