Mortality in lupus nephritis

Arthritis Rheum. 1979 Jul;22(7):764-9. doi: 10.1002/art.1780220712.

Abstract

The principal causes of death of 68 patients with lupus glomerulonephritis were reviewed. Renal failure (40%), vascular events (25%), and infections (16%) were the predominant causes. Diffuse proliferative glomerulonephritis was associated with an increased frequency of renal failure. A bimodal pattern of early deaths due to active lupus and sepsis and late deaths from vascular events was found superimposed on a constant rate of death from renal failure.

MeSH terms

  • Acute Kidney Injury / mortality
  • Adult
  • Bacterial Infections / mortality
  • Central Nervous System Diseases / mortality
  • Cerebrovascular Disorders / mortality
  • Death, Sudden / etiology
  • Glomerulonephritis / mortality
  • Heart Failure / mortality
  • Humans
  • Immunosuppression / adverse effects
  • Liver Diseases / mortality
  • Lupus Erythematosus, Systemic / mortality*
  • Maryland
  • Middle Aged
  • Nephritis / mortality*
  • Pulmonary Embolism / mortality
  • Time Factors