Adverse effects of phenobarbital on corticosteroid metabolism in patients with bronchial asthma

N Engl J Med. 1972 May 25;286(21):1125-8. doi: 10.1056/NEJM197205252862103.
No abstract available

Publication types

  • Clinical Trial
  • Controlled Clinical Trial

MeSH terms

  • Acetates / urine
  • Adolescent
  • Adrenal Cortex Hormones / metabolism*
  • Adult
  • Asthma / drug therapy*
  • Asthma / metabolism
  • Asthma / physiopathology
  • Chloroform / urine
  • Clinical Trials as Topic
  • Dexamethasone / blood
  • Dexamethasone / metabolism
  • Eosinophils
  • Female
  • Half-Life
  • Humans
  • Hydrocortisone / urine
  • Hydroxycorticosteroids / urine
  • Hydroxylation
  • Kinetics
  • Leukocyte Count
  • Male
  • Middle Aged
  • Phenobarbital / adverse effects*
  • Phenobarbital / therapeutic use
  • Placebos
  • Prednisone / metabolism
  • Spirometry
  • Tritium

Substances

  • Acetates
  • Adrenal Cortex Hormones
  • Hydroxycorticosteroids
  • Placebos
  • Tritium
  • Dexamethasone
  • Chloroform
  • Prednisone
  • Hydrocortisone
  • Phenobarbital