Intravenous injection in man of 9 -tetrahydrocannabinol and 11-OH- 9 -tetrahydrocannabinol

Science. 1972 Aug 18;177(4049):633-5. doi: 10.1126/science.177.4049.633.

Abstract

A microsuspension of Delta(9)-tetrahydrocannabinol and of its metabolic derivative 11-OH-Delta(9)-tetrahydrocannabinol has been prepared with 25 percent human serum albumin as the vehicle. Intravenous infusion of this preparation to humans indicates that both tetrahydrocannabinols are equally potent in producing the typical marihuana-like pschological and physiological effects.

Publication types

  • Clinical Trial
  • Comparative Study
  • Controlled Clinical Trial

MeSH terms

  • Adult
  • Cannabis / administration & dosage*
  • Clinical Trials as Topic
  • Dronabinol / administration & dosage
  • Dronabinol / pharmacology
  • Emotions / drug effects
  • Heart Rate / drug effects
  • Humans
  • Injections, Intravenous
  • Male
  • Pharmaceutical Vehicles
  • Phytotherapy*
  • Placebos
  • Serum Albumin

Substances

  • Pharmaceutical Vehicles
  • Placebos
  • Serum Albumin
  • Dronabinol