Pilus-specific, lipid-containing bacteriophages PR4 and PR772: comparison of physical characteristics of genomes

J Gen Virol. 1979 Oct;45(1):195-200. doi: 10.1099/0022-1317-45-1-195.

Abstract

The genomes of pilus-specific, lipid-containing phages PR4 and PR772 were studied electron microscopically. An identical mol. wt. of 10.9 x 10(6) was obtained. The genomes are unique (non-permuted) and have cohesive ends. From the similarities in size and denaturation maps of the genomes and failue to demonstrate non-homology in heteroduplexes, reported morphological ambiguities were clarified. The known serological difference between the phages could not be related to non-homology of their genomes. It is concluded that phages PR4 and PR772 are the same phage.

Publication types

  • Comparative Study

MeSH terms

  • Coliphages / analysis
  • Coliphages / genetics*
  • DNA, Viral / analysis*
  • Fimbriae, Bacterial / microbiology
  • Genes, Viral*
  • Lipids / analysis
  • Molecular Weight
  • Nucleic Acid Conformation
  • Nucleic Acid Denaturation
  • Nucleic Acid Heteroduplexes

Substances

  • DNA, Viral
  • Lipids
  • Nucleic Acid Heteroduplexes