Lactulose: a review of its therapeutic and pharmacological properties with particular reference to ammonia metabolism and its mode of action of portal systemic encephalopathy

Drugs. 1972;4(1):7-48. doi: 10.2165/00003495-197204010-00003.
No abstract available

Publication types

  • Review

MeSH terms

  • Adult
  • Aged
  • Ammonia / metabolism*
  • Animals
  • Constipation / drug therapy
  • Disaccharides* / adverse effects
  • Disaccharides* / pharmacology
  • Disaccharides* / therapeutic use
  • Disaccharides* / toxicity
  • Electroencephalography
  • Feces / analysis
  • Female
  • Hepatic Encephalopathy / drug therapy
  • Humans
  • Hydrogen-Ion Concentration
  • Intestines / drug effects
  • Intestines / microbiology
  • Liver Diseases / drug therapy*
  • Male
  • Middle Aged
  • Portal System
  • Sorbitol / therapeutic use
  • Swine
  • Time Factors

Substances

  • Disaccharides
  • Sorbitol
  • Ammonia