Appearance of specific colostrum antibodies after clinical infection with Salmonella typhimurium

Br Med J. 1974 Aug 3;3(5926):307-9. doi: 10.1136/bmj.3.5926.307.

Abstract

Colostrum and serum antibodies to Salmonella typhimurium have been found in three patients after clinical gastrointestinal infection during pregnancy. High levels of colostrum IgA agglutinins were directed specifically against both the flagellar and somatic antigens of the infective organism. The levels of colostrum agglutinating activity exceeded those found in the patients sera, while control colostrum gave negative results.

MeSH terms

  • Agglutination Tests
  • Antibodies, Bacterial / analysis*
  • Antibody Formation
  • Antigens, Bacterial / analysis
  • Colostrum / immunology*
  • Female
  • Fluorescent Antibody Technique
  • Gastrointestinal Diseases / immunology
  • Humans
  • Immunity, Maternally-Acquired
  • Immunoglobulin A / analysis
  • Pregnancy
  • Pregnancy Complications, Infectious / immunology*
  • Salmonella Infections / immunology*
  • Salmonella typhimurium / immunology*

Substances

  • Antibodies, Bacterial
  • Antigens, Bacterial
  • Immunoglobulin A