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, 6 (7), 2601-10

A Strategy of DNA Sequencing Employing Computer Programs

A Strategy of DNA Sequencing Employing Computer Programs

R Staden. Nucleic Acids Res.

Abstract

With modern fast sequencing techniques and suitable computer programs it is now possible to sequence whole genomes without the need of restriction maps. This paper describes computer programs that can be used to order both sequence gel readings and clones. A method of coding for uncertainties in gel readings is described. These programs are available on request.

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