Abstract
Stimulation and inhibition tests are proposed for evaluating prolactin secretion. Thyrotropin-releasing hormone (TRH) stimulates the release of prolactin from the pituitary. Chlorpromazine acts presumably at the hypothalamic level to increase prolactin secretion. L-Dopa (D,L-alpha-hydrazino-alpha-methyl-beta-[3,4-di-hydroxyphenyl]) has the opposite effect; it inhibits prolactin secretion and may be effective in suppressing galactorrhea.
MeSH terms
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Administration, Oral
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Adolescent
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Adult
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Child, Preschool
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Chlorpromazine / administration & dosage
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Chlorpromazine / pharmacology*
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Dihydroxyphenylalanine / administration & dosage
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Dihydroxyphenylalanine / pharmacology*
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Dihydroxyphenylalanine / therapeutic use
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Female
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Humans
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Injections, Intramuscular
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Injections, Intravenous
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Lactation Disorders / drug therapy*
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Male
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Pituitary Gland / drug effects*
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Pituitary Gland / metabolism
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Pregnancy
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Prolactin / antagonists & inhibitors
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Prolactin / blood
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Prolactin / metabolism*
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Radioimmunoassay
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Thyrotropin / blood
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Thyrotropin-Releasing Hormone / administration & dosage
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Thyrotropin-Releasing Hormone / pharmacology*
Substances
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Thyrotropin-Releasing Hormone
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Dihydroxyphenylalanine
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Prolactin
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Thyrotropin
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Chlorpromazine