Oxidative drug metabolism in liver microsomes from uremic rats

Kidney Int. 1972 Sep;2(3):152-8. doi: 10.1038/ki.1972.85.
No abstract available

MeSH terms

  • Acetanilides / metabolism*
  • Aminopyrine / metabolism*
  • Animals
  • Anisoles / metabolism
  • Blood Urea Nitrogen
  • Body Weight
  • Creatinine / blood
  • Cytochrome P-450 Enzyme System / metabolism
  • Cytochromes / metabolism
  • Dietary Carbohydrates / pharmacology
  • Hydroxylation
  • Injections, Intraperitoneal
  • Levulinic Acids / administration & dosage
  • Levulinic Acids / pharmacology
  • Liver / anatomy & histology
  • Male
  • Methylation
  • Microsomes, Liver / analysis
  • Microsomes, Liver / enzymology
  • Microsomes, Liver / metabolism*
  • Nephrectomy
  • Nitro Compounds / metabolism
  • Organ Size
  • Proteins / analysis
  • Rats
  • Uremia / metabolism*

Substances

  • Acetanilides
  • Anisoles
  • Cytochromes
  • Dietary Carbohydrates
  • Levulinic Acids
  • Nitro Compounds
  • Proteins
  • Aminopyrine
  • Cytochrome P-450 Enzyme System
  • Creatinine