Herbimycin, a new antibiotic produced by a strain of Streptomyces

J Antibiot (Tokyo). 1979 Apr;32(4):255-61. doi: 10.7164/antibiotics.32.255.

Abstract

Herbimycin, a new antibiotic, was isolated from the fermentation broth of Streptomyces hygroscopicus strain No. AM-3672, a soil isolate. The molecular formula of herbimycin was determined to be C30H42N2O9. Herbimycin was found to have potent herbicidal activity against most mono- and di-cotyledonous plants, especially against Cyperus microiria STEUD. However, Oryza sativa showed strong resistance to herbimycin.

MeSH terms

  • Animals
  • Anti-Bacterial Agents / biosynthesis*
  • Anti-Bacterial Agents / pharmacology
  • Chemical Phenomena
  • Chemistry, Physical
  • Herbicides / biosynthesis
  • Lethal Dose 50
  • Mice
  • Streptomyces / classification
  • Streptomyces / metabolism*

Substances

  • Anti-Bacterial Agents
  • Herbicides