Intravenous administration of glycopyrronium: effects on cardiac rate and rhythm

Anaesthesia. 1979 May;34(5):458-62. doi: 10.1111/j.1365-2044.1979.tb06324.x.

Abstract

Intravenous administration of glycopyrronium in doses up to 0.2 mg, was associated with minimal changes in cardiac rate and rhythm. Sinus arrhythmia, nodal rhythm and occasional atrial ectopics were the dysrhythmias observed. There were no accompanying changes in blood pressure.

MeSH terms

  • Adult
  • Depression, Chemical
  • Electrocardiography
  • Glycopyrrolate / administration & dosage*
  • Glycopyrrolate / pharmacology
  • Heart / drug effects
  • Heart Rate / drug effects
  • Humans
  • Injections, Intravenous
  • Pyrrolidines / administration & dosage*
  • Time Factors

Substances

  • Pyrrolidines
  • Glycopyrrolate