Analgesic effects of sublingual buprenorphine

Anaesthesia. 1979 May;34(5):463-7. doi: 10.1111/j.1365-2044.1979.tb06325.x.

Abstract

The analgesic effects of sublingually administered buprenorphine 0.4 mg have been compared with morphine 10 mg given intramuscularly in patients following operation. The results indicate a slower onset of action for buprenorphine but of much longer duration than morphine. There were no serious side effects or difference in their incidence between the two drugs.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Administration, Oral
  • Adult
  • Buprenorphine / administration & dosage
  • Buprenorphine / therapeutic use*
  • Drug Evaluation
  • Humans
  • Morphinans / therapeutic use*
  • Morphine / therapeutic use
  • Mouth Floor
  • Pain, Postoperative / drug therapy*

Substances

  • Morphinans
  • Buprenorphine
  • Morphine