Fatty acid composition of erythrocytes in hereditary spherocytosis

Br J Haematol. 1979 Jul;42(3):399-402. doi: 10.1111/j.1365-2141.1979.tb01148.x.

Abstract

The fatty acid distribution of the four major phospholipids has been determined in the erythrocytes of five patients with hereditary spherocytosis and in five control subjects. In contrast to a report by other workers, we are unable to confirm their findings of a defect in fatty acid chain lengthening activity leading to disappearance of long chain fatty acid conjugates of more than 20 carbon atoms in some of the phospholipid fractions.

MeSH terms

  • Erythrocytes / metabolism*
  • Fatty Acids / blood*
  • Humans
  • Phospholipids / blood
  • Spherocytosis, Hereditary / blood*

Substances

  • Fatty Acids
  • Phospholipids