The value of a tracer dose in predicting the kinetics of therapeutic doses of 131I in thyrotoxicosis

Br J Radiol. 1979 Sep;52(621):719-26. doi: 10.1259/0007-1285-52-621-719.

Abstract

The kinetics of tracer doses of 131I, assessed by measuring uptake and effective half-life, correlate well with the kinetics of therapy doses. The effective half-life was measured using thermoluminescent discs fixed to the patients' anterior neck surface. This method gives results comparable with those obtained using an uptake probe, and met with a good response by the patients. Using the kinetics of the tracer dose to assist prescription of radioiodine therapy would considerably reduce the spread of absorbed doses to the glands of a group of patients. The case for attempting more exact dosimetry in this field is reviewed.

MeSH terms

  • Half-Life
  • Humans
  • Hyperthyroidism / radiotherapy*
  • Iodine Radioisotopes / therapeutic use*
  • Kinetics
  • Radiotherapy Dosage

Substances

  • Iodine Radioisotopes