A high molecular weight inhibitor of Ca2+ -dependent neutral protease in rat brain

I Nishiura; K Tanaka; T Murachi

doi:10.1007/BF01949908

A high molecular weight inhibitor of Ca2+ -dependent neutral protease in rat brain

Experientia. 1979 Aug 15;35(8):1006-7. doi: 10.1007/BF01949908.

Authors

I Nishiura, K Tanaka, T Murachi

PMID: 477856
DOI: 10.1007/BF01949908

Abstract

An endogenous, heat-stable inhibitor of high mol. wt (approximately 3x10(5)) was found to be present in rat brain, which inhibited Ca2+-dependent neutral protease specifically but not due to its binding of Ca2+ in the medium .

MeSH terms

Animals
Brain / enzymology*
Brain Chemistry*
Calcium / pharmacology*
Kinetics
Peptide Hydrolases / metabolism*
Protease Inhibitors / isolation & purification*
Rats

Substances

Protease Inhibitors
Peptide Hydrolases
Calcium