[Correlation between cholesterol and lecithin in the blood and muscles and physiologic indices in rats developing in various stress states]

Fiziol Zh SSSR Im I M Sechenova. 1979 Jul;65(7):970-8.
[Article in Russian]

Abstract

Development female rats during the 1st year of life, under conditions of dynamic exercises caused starting from the 4th month, a decrease in the blood cholesterin and the raise of lecithin and lecithin--cholesterin index (L/Ch). No hypercholesterinemia common for the control animals develops by the 13th month in these animals. The cholesterin content increases in their muscles. Static loads launch less beneficent shifts of the above parameters. These rats reveal larger amount of the blood cholesterin along with its decrease in the muscles by the end of the 1st year. Under nociceptive effects the rats develop hypercholesterinemia and hypolecithinemia yet by the 7th month which accounts for a sharply reduced L/Ch index. At 13 months cholesterin is obviously decreased in the muscles of these rats. Resting energy expenditure is increased in these rats due to activated thyroid function and to a decrease in the cholinergic maintenance of regulation.

Publication types

  • English Abstract

MeSH terms

  • Acetylcholinesterase
  • Age Factors
  • Animals
  • Cholesterol / analysis*
  • Cholesterol / blood
  • Female
  • Growth
  • Heart Rate
  • Muscles / analysis*
  • Oxygen Consumption
  • Pain / physiopathology
  • Phosphatidylcholines / analysis*
  • Phosphatidylcholines / blood
  • Rats
  • Stress, Physiological / blood
  • Stress, Physiological / metabolism*
  • Stress, Physiological / physiopathology

Substances

  • Phosphatidylcholines
  • Cholesterol
  • Acetylcholinesterase