Some comparative effects of racemic methadone and its optical isomers in rodents

Res Commun Chem Pathol Pharmacol. 1974 Apr;7(4):651-62.
No abstract available

Publication types

  • Comparative Study

MeSH terms

  • Acetates / antagonists & inhibitors
  • Acetates / pharmacology
  • Administration, Oral
  • Analgesia
  • Animals
  • Dose-Response Relationship, Drug
  • Female
  • Injections, Subcutaneous
  • Isomerism
  • Lethal Dose 50
  • Male
  • Methadone / administration & dosage
  • Methadone / pharmacology*
  • Methadone / toxicity
  • Mice
  • Motor Activity / drug effects
  • Naloxone / pharmacology
  • Optical Rotation
  • Rats
  • Reaction Time / drug effects
  • Reflex / drug effects
  • Spasm / chemically induced
  • Tail

Substances

  • Acetates
  • Naloxone
  • Methadone