Absence of human placental lactogen in an otherwise uneventful pregnancy

Am J Obstet Gynecol. 1979 Oct 1;135(3):322-6. doi: 10.1016/0002-9378(79)90698-7.


Human placental lactogen (hPL) is commonly used in surveying the placental function during normal and pathologic pregnancies. This report describes a pregnancy where hPL could not be found in maternal serum or placental tissue. The pregnancy was in all other respects completely normal, ending with the birth of a normal baby. Some possible reasons and consequences of this unique event are discussed.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antibodies / analysis
  • Female
  • Humans
  • Infant, Newborn
  • Male
  • Placenta / ultrastructure
  • Placental Lactogen / deficiency*
  • Placental Lactogen / immunology
  • Placental Lactogen / physiology
  • Pregnancy*


  • Antibodies
  • Placental Lactogen