Abstract
Mutations to streptomycin resistance in Escherichia coli K12, when transferred to a C strain, can confer dependence on streptomycin. These alternatives in expression of the allele are probably a result of interaction between two ribosomal proteins.
MeSH terms
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Alleles*
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Bacterial Proteins / metabolism
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Drug Resistance, Microbial*
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Escherichia coli / metabolism*
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Genetics, Microbial
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Mutation*
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Pharmacogenetics
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Recombination, Genetic
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Ribosomes / metabolism
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Streptomycin / pharmacology*
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Transduction, Genetic
Substances
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Bacterial Proteins
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Streptomycin