Malignancy in a 19-year experience of adult celiac disease

Dig Dis Sci. 1979 Sep;24(9):684-8. doi: 10.1007/BF01314465.

Abstract

Malignancy has developed in 10 of 93 patients with celiac disease who attended this hospital from 1959 to 1978. Four patients developed lymphoma, 5 a squamous carcinoma of the esophagus, and 1 an adenocarcinoma of the ileum. Because the majority of patients were ingesting varying amounts of gluten at the time of their follow-up no conclusion can be drawn about the possible role of a gluten-free diet in the prevention of malignancy.

MeSH terms

  • Adenocarcinoma / complications*
  • Adenocarcinoma / epidemiology
  • Adolescent
  • Adult
  • Aged
  • Australia
  • Carcinoma, Squamous Cell / complications*
  • Carcinoma, Squamous Cell / epidemiology
  • Celiac Disease / complications*
  • Celiac Disease / diet therapy
  • Esophageal Neoplasms / complications*
  • Esophageal Neoplasms / epidemiology
  • Female
  • Glutens
  • Humans
  • Ileum
  • Intestinal Neoplasms / complications*
  • Intestinal Neoplasms / epidemiology
  • Lymphoma / complications*
  • Lymphoma / epidemiology
  • Male
  • Middle Aged
  • Risk

Substances

  • Glutens