Effect of pectin, guar gum, and wheat fibre on serum-cholesterol

Lancet. 1975 May 17;1(7916):1116-7. doi: 10.1016/s0140-6736(75)92503-9.

Abstract

36 G of wheat fibre, pectin, or guar gum was given over 2-week periods to healthy volunteers taking normal diet. Mean serum-cholesterol levels fell significantly while the volunteers were taking guar and pectin by 36-3 and 29-2 mg, per 100. respectively, but rose slightly after wheat fibre by 6-7, mg per 100., Attention should be focused on fruit and vegetable gels rather than wheat fibre in the search of natural hypocholesterolaemic agents.

Publication types

  • Clinical Trial
  • Comparative Study
  • Controlled Clinical Trial

MeSH terms

  • Adult
  • Anticholesteremic Agents*
  • Cholesterol / blood*
  • Galactans
  • Humans
  • Male
  • Mannans
  • Pectins / pharmacology*
  • Plant Extracts* / pharmacology
  • Plant Gums
  • Plants*
  • Polysaccharides / pharmacology*
  • Time Factors
  • Triticum*
  • Vegetables*

Substances

  • Anticholesteremic Agents
  • Galactans
  • Mannans
  • Plant Extracts
  • Plant Gums
  • Polysaccharides
  • Pectins
  • Cholesterol
  • guar gum