Effect of vitamin E on human sexual functioning

Arch Sex Behav. 1979 Sep;8(5):397-403. doi: 10.1007/BF01541196.


To investigate the claim that vitamin E can affect human sexual functioning, 1000-IU vitamin E capsules (alpha-tocopherol) were administered daily for 28 days in a double-blind placebo study. Thirty-five subjects in this pilot study reported daily responses to questionnaires on sexual arousal and behavior. No differences in sexual arousal or behavior were found between the two groups. The one significant difference was that the vitamin E subjects were more likely than the placebo subjects to report either positive or negative nonsexual effects.

Publication types

  • Clinical Trial
  • Controlled Clinical Trial

MeSH terms

  • Adult
  • Arousal / drug effects*
  • Double-Blind Method
  • Female
  • Humans
  • Male
  • Middle Aged
  • Pilot Projects
  • Placebos
  • Sexual Behavior / drug effects*
  • Vitamin E / pharmacology*


  • Placebos
  • Vitamin E