Syndrome of bilateral pheochromocytoma, medullary thyroid carcinoma and multiple neuromas. A possible regulatory defect in the differentiation of chromaffin tissue

N Engl J Med. 1968 Jul 4;279(1):1-7. doi: 10.1056/NEJM196807042790101.
No abstract available

MeSH terms

  • Adenoma / complications
  • Adrenal Gland Neoplasms / complications*
  • Adrenal Gland Neoplasms / genetics
  • Adrenal Gland Neoplasms / pathology
  • Adult
  • Amyloid / metabolism
  • Carcinoma / complications*
  • Carcinoma / pathology
  • Cell Differentiation
  • Chromaffin System / embryology
  • Facial Expression
  • Female
  • Humans
  • Lymphatic Metastasis
  • Male
  • Middle Aged
  • Neoplasm Metastasis
  • Neoplasms, Multiple Primary
  • Neurofibromatosis 1 / complications*
  • Neurofibromatosis 1 / genetics
  • Neurofibromatosis 1 / pathology
  • Palatal Neoplasms / complications
  • Pheochromocytoma / complications*
  • Pheochromocytoma / genetics
  • Pheochromocytoma / pathology
  • Thyroid Neoplasms / complications*
  • Thyroid Neoplasms / genetics
  • Thyroid Neoplasms / pathology
  • Thyroidectomy
  • Tongue Neoplasms / complications

Substances

  • Amyloid