Comparison of the drug metabolising ability of rat intestinal mucosal microsomes with that of liver

Biochem Pharmacol. 1979 Sep 15;28(18):2835-9. doi: 10.1016/0006-2952(79)90569-0.
No abstract available

Publication types

  • Comparative Study

MeSH terms

  • Animals
  • Cytochrome P-450 Enzyme System / metabolism*
  • Intestinal Mucosa / metabolism*
  • Kinetics
  • Male
  • Methylcholanthrene / pharmacology
  • Metyrapone / pharmacology
  • Microsomes / drug effects
  • Microsomes / metabolism*
  • Microsomes, Liver / drug effects
  • Microsomes, Liver / metabolism*
  • Mixed Function Oxygenases / metabolism*
  • Organ Specificity
  • Oxidoreductases / metabolism*
  • Phenobarbital / pharmacology
  • Proadifen / pharmacology
  • Rats

Substances

  • Methylcholanthrene
  • Cytochrome P-450 Enzyme System
  • Proadifen
  • Mixed Function Oxygenases
  • Oxidoreductases
  • Phenobarbital
  • Metyrapone