Rickettsial antibodies in multiple sclerosis

Br Med J. 1970 Jan 3;1(5687):30-2. doi: 10.1136/bmj.1.5687.30.

Abstract

The serum of subjects with multiple sclerosis or other degenerative neurological diseases and that of normal controls does not differ significantly in its content of antibodies to several rickettsial antigens. There is no evidence for a rickettsial aetiology of multiple sclerosis, and no grounds for an extended clinical trial of Le Gac's full method of treatment with antibiotics.

MeSH terms

  • Adult
  • Agglutination Tests
  • Anti-Bacterial Agents / therapeutic use
  • Antibodies / analysis*
  • Antigens
  • Coxiella / immunology
  • Female
  • Humans
  • Male
  • Multiple Sclerosis / blood
  • Multiple Sclerosis / drug therapy
  • Multiple Sclerosis / immunology*
  • Multiple Sclerosis / microbiology
  • Rickettsia / immunology*
  • Rickettsia prowazekii / immunology
  • Rickettsia typhi / immunology

Substances

  • Anti-Bacterial Agents
  • Antibodies
  • Antigens