Abstract
A mutant of Escherichia coli resembles its parent in taking up actinomycin after treatment with ethylenediaminetetraacetic acid but differs in that it survives this uptake and excretes actinomycin at an increased rate.
MeSH terms
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Carbon Isotopes
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Chromatography, Paper
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Dactinomycin / metabolism*
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Dactinomycin / pharmacology
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Drug Resistance, Microbial
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Edetic Acid / pharmacology
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Escherichia coli / drug effects
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Escherichia coli / growth & development
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Escherichia coli / metabolism*
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Genetics, Microbial
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Mutation*
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RNA, Bacterial / biosynthesis
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Uracil / metabolism
Substances
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Carbon Isotopes
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RNA, Bacterial
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Dactinomycin
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Uracil
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Edetic Acid