Evaluation of methods for estimating the dissociation constant of tight binding enzyme inhibitors

J Biol Chem. 1979 Dec 10;254(23):12104-9.
No abstract available

Publication types

  • Comparative Study
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Chickens
  • Enzyme Inhibitors* / pharmacology
  • Folic Acid Antagonists*
  • Humans
  • Liver / enzymology
  • Mathematics
  • Methods
  • Methotrexate / pharmacology
  • Mice
  • Neoplasms, Experimental / enzymology
  • Protein Binding
  • Rats
  • Sarcoma, Experimental / enzymology

Substances

  • Enzyme Inhibitors
  • Folic Acid Antagonists
  • Methotrexate