Detection of the sickle gene in the human fetus. Potential for intrauterine diagnosis of sickle-cell anemia

N Engl J Med. 1972 Jul 6;287(1):1-5. doi: 10.1056/NEJM197207062870101.
No abstract available

MeSH terms

  • Amniocentesis
  • Anemia, Sickle Cell / diagnosis*
  • Anemia, Sickle Cell / genetics
  • Blood Protein Electrophoresis
  • Carbon Isotopes
  • Chromatography
  • Electrophoresis
  • Female
  • Fetal Diseases / diagnosis*
  • Fetus / metabolism
  • Gestational Age
  • Globins / biosynthesis
  • Hemoglobins, Abnormal / analysis
  • Hemoglobins, Abnormal / biosynthesis
  • Humans
  • Leucine / metabolism
  • Methods
  • Methylcellulose
  • Placenta
  • Pregnancy
  • Tritium
  • Umbilical Cord

Substances

  • Carbon Isotopes
  • Hemoglobins, Abnormal
  • Tritium
  • Globins
  • Methylcellulose
  • Leucine