Generalized accumulation of neutral glycosphingolipids with GM2 ganglioside accumulation in the brain. Sandhoff's disease (variant of Tay-Sachs disease)

Am J Med. 1972 Jun;52(6):763-70. doi: 10.1016/0002-9343(72)90082-4.
No abstract available

MeSH terms

  • Brain / metabolism*
  • Brain / pathology
  • Gangliosides / metabolism*
  • Glycolipids / blood
  • Glycolipids / metabolism*
  • Glycolipids / urine
  • Humans
  • Infant
  • Lipidoses / blood
  • Lipidoses / metabolism*
  • Lipidoses / pathology
  • Lipidoses / urine
  • Liver / pathology
  • Male
  • Myocardium / pathology
  • Sphingolipids / blood
  • Sphingolipids / metabolism*
  • Sphingolipids / urine

Substances

  • Gangliosides
  • Glycolipids
  • Sphingolipids