Sarcoid reactions and sarcoidosis in Hodgkin's disease and other malignant lymphomata

Br J Cancer. 1972 Apr;26(2):120-3. doi: 10.1038/bjc.1972.18.


Nineteen cases of malignant lymphomata were selected for study from a group of about 1500 collected cases of malignant lymphomata because they showed histological evidence of non-infectious epithelioid-cell granulomata in one or more tissues.In the 19 cases selected, 5 cases of systemic sarcoidosis, 4 cases of an associated malignancy, 1 pre-malignant condition, and 1 case of an auto-immune disease were found.This remarkable association of sarcoid reactions or sarcoidosis with malignant lymphomata and associated malignancies seems to justify speculation on the possibility of a common aetiological factor, e.g. in the form of an altered immune reaction.

MeSH terms

  • Adult
  • Aged
  • Autoimmune Diseases
  • Child
  • Female
  • Hodgkin Disease / complications*
  • Hodgkin Disease / etiology
  • Humans
  • Lymphoma / complications*
  • Male
  • Middle Aged
  • Prednisone / therapeutic use
  • Sarcoidosis / complications*
  • Sarcoidosis / drug therapy
  • Sarcoidosis / etiology


  • Prednisone