Inhibition of catechol-O-methyltransferase by S-adenosylhomocysteine and S-adenosylhomocysteine sulfoxide, a potential transition-state analog

Biochem Pharmacol. 1972 Apr 15;21(8):1200-3. doi: 10.1016/0006-2952(72)90114-1.
No abstract available

MeSH terms

  • Adenosine*
  • Animals
  • Carbon Isotopes
  • Catechol O-Methyltransferase Inhibitors
  • Chemical Phenomena
  • Chemistry
  • Homocysteine*
  • Kinetics
  • Liver / enzymology
  • Methylation
  • Methyltransferases / antagonists & inhibitors*
  • Rats
  • Structure-Activity Relationship
  • Sulfoxides

Substances

  • Carbon Isotopes
  • Catechol O-Methyltransferase Inhibitors
  • Sulfoxides
  • Homocysteine
  • Methyltransferases
  • Adenosine