Application of ion-pair methods to drug extraction from biological fluids. II. Quantitative determination of biguanides in biological fluids and comparison of protein binding estimates

MeSH terms

• Animals
• Biguanides / analysis*
• Biguanides / blood
• Biguanides / cerebrospinal fluid
• Biguanides / metabolism
• Chemistry, Pharmaceutical
• Cresols
• Dialysis
• Dogs
• Erythrocytes / metabolism
• Filtration
• Humans
• Hydrogen-Ion Concentration
• Ions
• Mathematics
• Metformin / blood
• Phenformin / blood
• Protein Binding*
• Solvents
• Spectrophotometry