The significance of lymphocytic infiltration in neuroblastoma

Br J Cancer. 1972 Aug;26(4):321-30. doi: 10.1038/bjc.1972.43.


A study of the significance of lymphocytic infiltration was made in a retrospective series of 23 primary neuroblastomata. The degree of lymphocytic infiltration was estimated and scored in 5 categories. Non-parametric rank order statistical methods were used to establish quantitative correlations, particularly with the duration of survival. A significant positive correlation was found both in infancy and childhood. It was found, unexpectedly, that the presence of metastases did not invalidate the correlation between lymphocyte score and survival.

MeSH terms

  • Adolescent
  • Analysis of Variance
  • Cell Count
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Infant
  • Lymphocytes*
  • Male
  • Mathematics
  • Neoplasm Metastasis
  • Neuroblastoma / pathology*
  • Prognosis
  • Statistics as Topic