Congenital oligonephronic renal hypoplasia with hypertrophy of nephrons (oligonephronia)

Arch Dis Child. 1971 Jun;46(247):321-6. doi: 10.1136/adc.46.247.321.


Four patients with oligonephronia are described. The clinical picture was that of a progressive renal insufficiency, but the time of onset and severity varied from one case to another. One patient had oligonephronia of one kidney and aplasia of the other kidney. In another patient a familial syndrome of multiple congenital anomalies was observed. In a sib of the latter patient, a simple unilateral renal hypoplasia was discovered.

MeSH terms

  • Abnormalities, Multiple
  • Child
  • Child, Preschool
  • Dilatation
  • Female
  • Glomerular Filtration Rate
  • Humans
  • Hypertrophy
  • Infant
  • Infant, Newborn
  • Kidney Diseases / complications
  • Kidney Diseases / congenital*
  • Kidney Diseases / pathology
  • Kidney Failure, Chronic
  • Kidney Glomerulus / pathology
  • Kidney Tubules / pathology
  • Male