Smoking and gastric juice volume in outpatients

Can Anaesth Soc J. 1979 Jul;26(4):328-30. doi: 10.1007/BF03006296.


The volumes and pH of gastric juice in 26 outpatients presenting for dental surgery were measured by simple aspiration through a nasogastric tube introduced after the induction of anaesthesia. The average volume in these patients who were non-smokers was 9 ml and in those patients who had smoked on the day of the operation was 19 ml. Four of the smokers had more than 25 ml of gastric juice with a pH of 2.0 or less. It is suggested that out-patients who smoke would benefit from prophylaxis such as oral antacids or metoclopramide before anaesthesia.

MeSH terms

  • Adult
  • Anesthesia, Dental
  • Anesthesia, General
  • Antacids / therapeutic use
  • Gastric Acidity Determination
  • Gastric Juice / metabolism*
  • Gastroesophageal Reflux / prevention & control
  • Humans
  • Metoclopramide / therapeutic use
  • Smoking / physiopathology*
  • Tooth Extraction


  • Antacids
  • Metoclopramide