Brain serotonin content: increase following ingestion of carbohydrate diet

Science. 1971 Dec 3;174(4013):1023-5. doi: 10.1126/science.174.4013.1023.

Abstract

In the rat, the injection of insulin or the consumption of carbohydrate causes sequential increases in the concentrations of tryptophan in the plasma and the brain and of serotonin in the brain. Serotonin-containing neurons may thus participate in systems whereby the rat brain integrates information about the metabolic state in its relation to control of homeostatis and behavior.

MeSH terms

  • Animals
  • Blood Glucose / analysis
  • Body Weight
  • Brain Chemistry* / drug effects
  • Dietary Carbohydrates*
  • Insulin / pharmacology
  • Male
  • Organ Size
  • Rats
  • Serotonin / analysis*
  • Time Factors
  • Tryptophan / analysis
  • Tryptophan / blood
  • Tyrosine / blood

Substances

  • Blood Glucose
  • Dietary Carbohydrates
  • Insulin
  • Serotonin
  • Tyrosine
  • Tryptophan