[Adverse effects of some modern drugs on the visual apparatus]

Cesk Oftalmol. 1971 Nov;27(6):367-73.
[Article in Czech]


PIP: The pharmaceutical industry manufactures tremendous amounts of new medical preparations every year, many of which cause reversible as well as irreversible damage to the visual apparatus. The older preparations affecting the eye are: organic compounds of arsenic, classic antimalarial medications (quinine and its derivatives), and classic anti helminthics. The modern preparations are: synthetic antimalarials (the most effective being colagenose), psychopharmaceutics, tuberculostatics, and glucocorticoids. The most dangerous of these are the synthetic antimalarials, e.g., Resochin, Nivaquin, Aralen, Plaquenil, Kamochin, Delagil, Quimercyl, and Hydrochloroquin. Another group that can cause toxi retinopathy are the psychopharmaceutics, especially phenathiasine, and in the group of tuberculostatics, Etambutol, INH, and perhaps even PAS and streptomycin. Glucocorticoids, can be very harmful, especially when applied locally at the beginning of the retina epithelium defect. When prescribing any of these medications, the physician should be aware of their side effects on the visual apparatus and should examine the patient for its symptoms.

Publication types

  • English Abstract

MeSH terms

  • Anthelmintics / adverse effects
  • Anti-Bacterial Agents / adverse effects
  • Anti-Inflammatory Agents / adverse effects
  • Anticoagulants / adverse effects
  • Anticonvulsants / adverse effects
  • Antimalarials / adverse effects
  • Contraceptives, Oral / adverse effects
  • Drug-Related Side Effects and Adverse Reactions*
  • Eye / drug effects*
  • Eye Diseases / chemically induced*
  • Humans
  • Hypoglycemic Agents / adverse effects
  • Vision, Ocular / drug effects*


  • Anthelmintics
  • Anti-Bacterial Agents
  • Anti-Inflammatory Agents
  • Anticoagulants
  • Anticonvulsants
  • Antimalarials
  • Contraceptives, Oral
  • Hypoglycemic Agents