Influence of hydrophobic character on the relative rate of oxidation of drugs by rat liver microsomes

J Med Chem. 1971 Sep;14(9):777-9. doi: 10.1021/jm00291a600.
No abstract available

MeSH terms

  • Aniline Compounds
  • Animals
  • Barbiturates
  • Caffeine
  • Chemical Phenomena
  • Chemistry, Physical
  • Chlorine
  • Codeine
  • Ephedrine
  • Fatty Alcohols
  • Hexobarbital
  • Kinetics
  • Male
  • Mathematics
  • Microsomes, Liver / enzymology*
  • Mixed Function Oxygenases
  • Naphthalenes
  • Oxidoreductases*
  • Phenobarbital
  • Physostigmine
  • Rats
  • Solubility
  • Structure-Activity Relationship

Substances

  • Aniline Compounds
  • Barbiturates
  • Fatty Alcohols
  • Naphthalenes
  • Caffeine
  • Chlorine
  • Physostigmine
  • Hexobarbital
  • Mixed Function Oxygenases
  • Oxidoreductases
  • Ephedrine
  • Codeine
  • Phenobarbital