Thymidylate synthetase. Model studies of inhibition by 5-trifluoromethyl-2'-deoxyuridylic acid

Biochemistry. 1971 Sep 14;10(19):3598-607. doi: 10.1021/bi00795a018.
No abstract available

MeSH terms

  • Acylation
  • Alkylation
  • Amines / chemical synthesis
  • Azides / chemical synthesis
  • Carboxylic Acids / chemical synthesis
  • Chemical Phenomena
  • Chemistry
  • Chromatography, Paper
  • Chromatography, Thin Layer
  • Deoxyribonucleotides
  • Fluorine
  • Hydrocarbons, Halogenated
  • Hydrogen-Ion Concentration
  • Hydrolysis
  • Kinetics
  • Mathematics
  • Methylation
  • Methyltransferases / antagonists & inhibitors*
  • Models, Chemical
  • Spectrophotometry
  • Uracil / chemical synthesis
  • Uracil Nucleotides*

Substances

  • Amines
  • Azides
  • Carboxylic Acids
  • Deoxyribonucleotides
  • Hydrocarbons, Halogenated
  • Uracil Nucleotides
  • Fluorine
  • Uracil
  • Methyltransferases