[Plasma aldosterone and renin activity in hypopituitarism (author's transl)]

Ann Endocrinol (Paris). 1979 Jul-Aug;40(4):433-4.
[Article in French]


Plasma renin activity (P.R.A.) and plasma aldosterone were measured in twelve patients having hypopituitarism. Both mean values of this group were significantly lower than in normal subjects (P.R.A. recumbent: p less than 0.001, upright: p less than 0.001, plasma aldosterone: recumbent: p less than 0.02, upright: p less than 0.005). Hyporeninism is a controversed feature in hypopituitarism. Our preliminary data suggest that it is not directly correlated to ACTH or cortisol deficiency. Nevertheless it may explain the hypoaldosteronism prior reported in such patients.

Publication types

  • English Abstract

MeSH terms

  • Adrenal Cortex Hormones / therapeutic use
  • Aldosterone / blood*
  • Cosyntropin / pharmacology
  • Humans
  • Hyponatremia / blood
  • Hypopituitarism / blood*
  • Hypopituitarism / drug therapy
  • Pituitary Hormones, Anterior / deficiency
  • Renin / blood*


  • Adrenal Cortex Hormones
  • Pituitary Hormones, Anterior
  • Cosyntropin
  • Aldosterone
  • Renin