Medicinal iron to low birth weight infants

Acta Paediatr Scand. 1979 Sep;68(5):705-8. doi: 10.1111/j.1651-2227.1979.tb18442.x.


Serum ferritin concentrations were measured during the first 6 months of life in 28 low birth weight infants (mean birth weight 1820 g range 900-2460; mean gestational age 34 weeks range 29-37) fed a standard formula fortified with ferrous sulphate. Fifteen of the infants received supplementary medicinal iron (ferrous succinate) from 3 weeks of age, and 13 only from 2 months of age. All were given vitamin E from 10 days of age. The serum ferritin values did not differ between the groups at 1-2 days, 8-10 weeks or at 6 months. Furthermore, there were no signs of hyperhaemolysis at 8-10 weeks in the group receiving medicinal iron early. The data indicate that the iron content in the formula is sufficient until 2 months of age, but also that thereis no disadvantage in starting medicinal iron at 3 weeks of age, if the diet is sufficient in vitamin E.

MeSH terms

  • Breast Feeding
  • Female
  • Ferritins / blood*
  • Ferrous Compounds / administration & dosage
  • Ferrous Compounds / therapeutic use*
  • Food, Fortified
  • Humans
  • Infant Food*
  • Infant, Low Birth Weight*
  • Infant, Newborn
  • Iron / therapeutic use*
  • Male
  • Sulfates / administration & dosage
  • Sulfates / therapeutic use
  • Vitamin E / administration & dosage


  • Ferrous Compounds
  • Sulfates
  • Vitamin E
  • ferrous sulfate
  • ferrous succinate
  • Ferritins
  • Iron