Abstract
A fraction of the covalently closed mitochondrial DNA in mouse L cells contains a replicated heavy-strand segment that is hydrogen bonded to the circular light strand. The inserted single strand is dissociable from the circular duplex at an elevated temperature.
MeSH terms
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Animals
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Carbon Isotopes
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Cell Fractionation
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Centrifugation, Density Gradient
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DNA / analysis*
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DNA / isolation & purification
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Hot Temperature
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L Cells
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Mice
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Microscopy, Electron
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Mitochondria / analysis*
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Molecular Weight
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Nucleic Acid Hybridization
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Protein Conformation*
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Thymidine
Substances
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Carbon Isotopes
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DNA
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Thymidine