[A study of H-2 mutations in mice. V. Detection of mutations M505, Hzl and M506 in the host vs transplant reaction]

Genetika. 1975;11(10):30-2.
[Article in Russian]

Abstract

H-2 mutant/normal pairs of congenic mouse strains C57BL/6equilibriumB6.M505 (H-2Kbd), C57BL/6equilibriumB6.C(Hz1) (H-2Kba) and A.CAequilibriumA.CA(M506) (H-2fa) were studied in the graft versus host assay. All the three mutations were expressed in these tests as gain and loss of H-2 antigen. The data obtained confirm an earlier suggestion that the H-2K antigenic molecule bears antigenic determinants which could be detected by a variety of immunological techniques.

Publication types

  • English Abstract

MeSH terms

  • Animals
  • Graft vs Host Reaction / genetics*
  • Graft vs Host Reaction / immunology
  • Histocompatibility Antigens*
  • Mice
  • Mice, Inbred Strains
  • Mutation*
  • Spleen / immunology
  • Spleen / transplantation*
  • Transplantation, Homologous

Substances

  • Histocompatibility Antigens