Leukocyte bactericidal activity in chronic granulomatous disease: correlation of bacterial hydrogen peroxide production and susceptibility to intracellular killing

J Bacteriol. 1969 Oct;100(1):531-2. doi: 10.1128/jb.100.1.531-532.1969.

Abstract

Susceptibility of bacteria to intracellular killing by polymorphonuclear leukocytes from a patient with chronic granulomatous disease could be correlated with bacterial hydrogen peroxide production.

MeSH terms

  • Bacteria / enzymology
  • Bacteria / metabolism*
  • Blood Bactericidal Activity*
  • Catalase / metabolism
  • Chronic Disease
  • Granuloma / blood*
  • Humans
  • Hydrogen Peroxide / biosynthesis*
  • Infant, Newborn
  • Infant, Newborn, Diseases / blood*
  • Infections / blood*
  • Leukocytes*
  • Lymphadenitis / blood*

Substances

  • Hydrogen Peroxide
  • Catalase