The Effect of Organic Acids on Renal Clearance of Methotrexate in Man

Clin Pharmacol Ther. Nov-Dec 1969;10(6):849-57. doi: 10.1002/cpt1969106849.

MeSH terms

  • Aminohippuric Acids / metabolism
  • Aminohippuric Acids / pharmacology*
  • Biological Transport, Active / drug effects
  • Blood Proteins / metabolism
  • Carbon Isotopes
  • Colorimetry
  • Female
  • Glomerular Filtration Rate*
  • Humans
  • Inulin / metabolism
  • Kidney Tubules / metabolism
  • Leukemia / metabolism
  • Male
  • Methotrexate / metabolism*
  • Middle Aged
  • Neoplasms / metabolism
  • Protein Binding / drug effects
  • Sodium Salicylate / pharmacology*
  • Sulfisoxazole / pharmacology*
  • Tritium

Substances

  • Aminohippuric Acids
  • Blood Proteins
  • Carbon Isotopes
  • Tritium
  • Sulfisoxazole
  • Inulin
  • Sodium Salicylate
  • Methotrexate