[The anti-allergic effect of an oral calcium preparation. Controlled double-blind study]

Fortschr Med. 1979 Sep 20;97(35):(1537-9).
[Article in German]


The effect of an orally applied calcium preparation (Frubiase Calcium forte) was investigated and compared with a placebo in 20 adolescent patients submitted to a random double-blind test on the immediate allergic reaction. The prick test with histamine and grass pollen mixed extract showed a highly significant statistical decrease (p less than 0,001) of wheal extension after an oral dose 1 x 6 Frubiase Calcium forte fluid ampoules, when compared to the test before application.

Publication types

  • Clinical Trial
  • English Abstract
  • Randomized Controlled Trial

MeSH terms

  • Administration, Oral
  • Adolescent
  • Calcium / administration & dosage
  • Calcium / therapeutic use*
  • Drug Evaluation
  • Humans
  • Hypersensitivity, Immediate / drug therapy*
  • Skin Tests


  • Calcium