Identification of a new allele of Es-I segregating in an inbred strain of mice

Biochem Genet. 1979 Aug;17(7-8):577-83. doi: 10.1007/BF00502119.

Abstract

A new allele of Es-1, designated Es-1e, has been identified in the mouse. This allele was discovered segregating among the progeny of a strain DBA/2J male and is apparently the result of a spontaneous mutation within this strain. Genetic analyses have shown that this mutation is heritable and, further, that both heterozygous and homozygous progeny are viable and fertile. To date, no discernible deleterious effects have been identified as associated with this mutation.

MeSH terms

  • Alleles
  • Animals
  • Electrophoresis, Starch Gel
  • Esterases / blood
  • Esterases / genetics*
  • Female
  • Kidney / enzymology
  • Male
  • Mice
  • Mice, Inbred DBA / genetics*
  • Mutation*
  • Phenotype

Substances

  • Esterases