Inactivation of penicillins by carbohydrate solutions at alkaline pH

N Engl J Med. 1970 Jul 16;283(3):116-9. doi: 10.1056/NEJM197007162830302.
No abstract available

MeSH terms

  • Allergens
  • Bicarbonates
  • Biological Assay
  • Buffers
  • Carbohydrates* / pharmacology
  • Drug Hypersensitivity / etiology
  • Drug Stability
  • Glucose
  • Humans
  • Hydrogen-Ion Concentration*
  • Penicillin G / antagonists & inhibitors
  • Penicillins / adverse effects
  • Penicillins / antagonists & inhibitors*
  • Penicillins / pharmacology
  • Solutions
  • Staphylococcus / drug effects
  • Staphylococcus / growth & development
  • Sucrose
  • Temperature
  • Time Factors

Substances

  • Allergens
  • Bicarbonates
  • Buffers
  • Carbohydrates
  • Penicillins
  • Solutions
  • Sucrose
  • Glucose
  • Penicillin G